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Imine reductase (IRED)
About Ine reductase
ES-IRED: Gulu la ma enzyme omwe amalimbikitsa kuchepetsa kwa C=N bond ku CN bond. Ndi la redox enzyme, yokhala ndi coenzyme NADPH yoyendetsera hydrogen. Malinga ndi zomwe chiral amakonda, amatha kugawidwa m'magulu a R-IRED ndi S-IRED. Syncozymes adapanga ma imine reductase 15 (numbIRED ES-IRED-101-ES-IRED-115), omwe angagwiritsidwe ntchito kwambiri pochepetsa regioselective ndi stereoselective ya imines kuti akonze ma chiral amines.
Mtundu wa catalytic reaction:
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Imelo:lchen@syncozymes.com
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Nitrile reductase (NRED)
Zokhudza Nitrile reductase
Pali mitundu itatu ya mankhwala a NRED enzyme (Nambala monga ES-NRED101~ ES-NRED103) yopangidwa ndi SyncoZymes. NRED imatha kuyambitsa kuchepa kwa gulu la nitrile kukhala amine. Mu catalysis, NADPH imafunika ngati chonyamulira hydrogen.
Nitrile reductasecatalytic reaction mtundu
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Leucine Dehydrogenase (LeuDH)
Zokhudza Leucine dehydrogenase
Pali mtundu umodzi wa mankhwala a enzyme a LeuDH (Nambala monga ES-LeuDH-101) omwe adapangidwa ndi SyncoZymes. LeuDH imatha kuyambitsa ammoniation yochepetsa mphamvu ya 4-methylbutanoic acid (mchere) kupita ku L-leucine kapena okosijeni ya leucine kupita ku 4-methylbutanoic acid. ES-LeuDH imathanso kuyambitsa mphamvu yochepetsa mphamvu ya α-keto acids yokhala ndi kapangidwe kofanana kuti ikonzekere zotumphukira za amino acid zofanana. Mu njira ya catalysis, NADH ndiyofunikira ngati chonyamulira hydrogen.
Leucine dehydrogenase mtundu wa catalytic reaction
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Threonine deaminase (TDA)
About Threonine deaminase
ES-TDA (Threonine deaminase): puloteni ya pyridoxal phosphate yomwe imayambitsa kuchotsedwa kwa threonine kuti ipange 2-ketobutyric acid ndi ammonia. Pyridoxal 5-phosphate ndi yofunika ngati coenzyme mu dongosolo lothandizira. Pali mtundu umodzi wokha wa mankhwala a TDA enzyme (Nambala monga ES-TDA) yopangidwa ndi SyncoZymes, yomwe ingagwiritsidwe ntchito kukonzekera 2-ketobutyric acid kapena zotumphukira zake kuchokera ku threonine.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Amine Dehydrogenase (AmDH)
Zokhudza Amine Dehydrogenase
ES-AmDH (Amine Dehydrogenase): enzyme yomwe ingathandize kupanga ammoniation ya gulu la carbonyl ndikulichepetsa kukhala gulu la amino. Ndi enzyme yodalira coenzyme NADH, ndipo NADH imagwira ntchito ngati chotumizira hydrogen. Pali mitundu inayi ya zinthu za enzyme ya AmDH (Nambala monga ES-AmDH101 ~ ES-AmDH104) yopangidwa ndi SyncoZymes, yomwe ingagwiritsidwe ntchito mu regioselective kapena stereoselective reductive amination ya aldehydes ndi ketones.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Nucloside phosphorylse (NP)
About nucleoside phosphorylse
Pali mitundu itatu ya zinthu zopangidwa ndi enzyme ya NP (Nambala monga ES-NP-101~ ES-NP-103) zomwe zapangidwa ndi SyncoZymes. ES-NP-101 ndi purine nucleoside phosphorylase, ES-NP-102 ndi ES-NP-103 ndi pyrimidine nucleoside phosphorylase. Nucleosidephosphorylase imatha kuwononga ma nucleosides kukhala maziko ndi pentose phosphate. Nucleoside phosphorylase ikhoza kugawidwa m'magulu awiri: purine nucleoside phosphorylase ndi pyrimidine nucleoside phosphorylase malinga ndi zomwe ma nucleoside bases amakonda. Purine nucleoside phosphorylase imatha kusintha adenosine kukhala adenine, inosine kukhala hypoxanthine, guanosine kukhala guanine, ndikupanga ribose phosphate nthawi imodzi. Pyrimidine nucleoside phosphorylase imatha kusintha uridine kukhala uracil ndikupanga ribose phosphate.
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Hydroaminase (HAM)
Zokhudza Hydroaminase
Pali mitundu iwiri ya mankhwala a HAM enzyme (Nambala monga ES-HAM-101~ ES-HAM-102) yopangidwa ndi SyncoZymes. HAM imatha kuyambitsa ammonia ya enoic acid kapena zotumphukira zake kuti ipange chiral amino acid. HAM ingagwiritsidwe ntchito kupanga chiral amino acid (kapena chiral amines) kuchokera ku enoic acids (kapena alkenes). Wopereka ammonia, monga madzi a ammonia kapena mchere wa ammonium, ndi wofunikira.
Hydroaminase catalytic reaction mtundu
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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CALB Yosayenda
CALB
Lipase B yopangidwanso kuchokera ku Candida antarctica (CALB) imapangidwa pogwiritsa ntchito kuwiritsa pansi pa madzi pogwiritsa ntchito Pichia pastoris yosinthidwa majini.
CALB ingagwiritsidwe ntchito mu gawo la madzi kapena gawo lachilengedwe lothandizira esterification, esterolysis, transesterification, ring opening polyester synthesis, aminolysis, hydrolysis of amides, acylation of amines ndi addition reaction.
CALB ili ndi kusankha kwakukulu kwa chiral komanso kusankha malo, kotero ingagwiritsidwe ntchito kwambiri mu kukonza mafuta, chakudya, mankhwala, zodzoladzola ndi mafakitale ena a mankhwala.
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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NADH oxidase (NOX)
Zokhudza NADH oxidase
ES-NOX (NADH oxidase): NOX imayambitsa okosijeni wa NADH kukhala NAD+, ndipo ndi ya oxidoreductase. Mu ndondomeko ya okosijeni, O2 ndi yofunika ngati okosijeni, ndipo imachepetsedwa kukhala H2O kapena H2O2. Pali mitundu inayi ya zinthu za NOX enzyme (ES-NOX-101~ES-NOX-104) zomwe zapangidwa ndi kampani yathu, zomwe zingagwiritsidwe ntchito pokonzanso okosijeni wa coenzyme NAD+.
Mtundu wa catalytic reaction:
or
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Phenylalanine ammonia lyase (PAL)
About Phenylalanine ammonia lyase
ES-PAL: Gulu la ma enzyme omwe amachititsa kuti L-phenylalanine ichotsedwe mwachindunji kukhala transcinnamic acid. Syncozymes adapanga zinthu 10 za phenylalanine ammonia lyase (yolembedwa ndi manambala a ES-PAL-101~ES-PAL-110), zomwe zingagwiritsidwe ntchito pochotsa kapena kubwezera phenylalanine ndi zotumphukira zake.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Katalase (CAT)
Zokhudza Catalase
ES-CAT (Catalase): imayambitsa kuwonongeka kwa H2O2 kukhala mpweya ndi madzi. Imapezeka makamaka mu mitochondria, endoplasmic reticulum, chiwindi cha nyama ndi maselo ofiira a magazi, makamaka m'chiwindi chomwe chili ndi kuchuluka kwakukulu, zomwe zimapangitsa kuti thupi liziteteza ku ma antioxidants. Mu biocatalysis, imagwiritsidwa ntchito kwambiri kuchotsa hydrogen peroxide yomwe imachokera ku reaction ndikuchepetsa kuletsa ndi kuletsa kwa enzyme ndi hydrogen peroxide. Pali mtundu umodzi wokha wa zinthu za enzyme za CAT zomwe zimapangidwa ndi SyncoZymes (Nambala monga ES-CAT).
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Lysine oxidase (LO)
Zokhudza Lysine oxidase
ES-LO (Lysine oxidase): imayambitsa okosijeni wa L-lysine kukhala 6-amino-2-oxohexanoic acid (kapena lactone yake). Pali mtundu umodzi wokha wa LO enzyme product (Nambala monga ES-LO) yopangidwa ndi SyncoZymes.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
