Imine reductase (IRED)
Kufotokozera Kwachidule:
Za Imine reductase
ES-IRED: Gulu la michere yomwe imathandizira kuchepetsa C=N chomangira ku CN chomangira.Ndi ya redox enzyme, yokhala ndi coenzyme NADPH yoyendetsa ma hydrogen.Malinga ndi zokonda zachiral za zinthuzo, zitha kugawidwa kukhala R-IRED ndi S-IRED.Ma syncozymes adapanga 15 imine reductases (nambala ES-IRED-101-ES-IRED-115), yomwe ingagwiritsidwe ntchito kwambiri pochepetsa regioselective ndi stereoselective ya imines kukonzekera ma chiral amines.
Mtundu wa Catalytic reaction:
Mobile/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
| Ma enzyme | Kodi katundu | Kufotokozera |
| Enzyme Powder | ES-IRED-101~ ES-IRED-114 | seti ya 14 Imine Reductase, 50 mg iliyonse |
| 96-Chabwino Enzyme Screening Kit | ES-IRED-1400 | seti ya 14 Imine Reductase, 1 mg iliyonse |
★ Kukhazikika kwa gawo lapansi.
★ Kusankha kwamphamvu kwachiral.
★ Kutembenuka kwakukulu.
★ Zogulitsa zochepa.
★ Mkhalidwe wofatsa.
★ Okonda zachilengedwe.
➢ Nthawi zambiri, kachitidwe kachitidwe kamayenera kukhala ndi gawo lapansi, yankho la buffer, enzyme, coenzyme, ndi coenzyme regeneration system.
➢ Mitundu yonse ya ma ES-IREDs ofanana ndi momwe zinthu zilili bwino ziyenera kuwerengedwa payekhapayekha.
➢ Malo okhala ndi zinthu zambiri kapena zinthu zomwe zili nazo zitha kulepheretsa ES-IRED kugwira ntchito.Komabe, zoletsazo zitha kumasulidwa ndikuwonjezera batch ya gawo lapansi.
Chitsanzo 1(Biosynthesis of chiral 2-methyl pyrrolidine)(1):
Chitsanzo 2(Biosynthesis of secondary amine)(2):
Chitsanzo 3 (Kuchepetsa kwa Cyclic Imines)(3):
Sungani zaka 2 pansi -20 ℃.
Osakhudzana ndi zinthu zowopsa monga: kutentha kwambiri, kutsika / kutsika pH komanso zosungunulira za organic.
1. Scheller PN, Fademrecht S, Hofelzer S, et al.ChemBioChem, 2014, 15, 2201-2204.
2. Wetzl D, Gand M, Ross A, et al.ChemCatChem, 2016, 8, 2023-2026.
3. Li H, Luan ZJ, Zheng GW, et al.Adv.Synth.Catal.2015, 357, 1692-1696.
