Amine Dehydrogenase (AmDH)
Kufotokozera Kwachidule:
Za Amine Dehydrogenase
ES-AmDH (Amine Dehydrogenase): puloteni yomwe imatha kuyambitsa ammoniation ya gulu la carbonyl ndikuchepetsa kukhala gulu la amino.Ndi coenzyme NADH yodalira enzyme, ndipo NADH imagwira ntchito ngati hydrogen transmitter.Pali mitundu inayi ya mankhwala a enzyme ya AmDH (Nambala monga ES-AmDH101～ES-AmDH104) yopangidwa ndi SyncoZymes, yomwe ingagwiritsidwe ntchito mu regioselective kapena stereoelective reductive amination ya aldehydes ndi ketoni.
Mtundu wa Catalytic reaction:
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Imelo:lchen@syncozymes.com
★ Kukhazikika kwa gawo lapansi.
★ Kusankha kwamphamvu kwachiral.
★ Kutembenuka kwakukulu.
★ Zogulitsa zochepa.
★ Mkhalidwe wofatsa.
★ Okonda zachilengedwe.
➢ Nthawi zambiri, kachitidwe kachitidwe kamayenera kukhala ndi gawo lapansi, njira yotchinga, enzyme, coenzyme ndi coenzyme regeneration system (mwachitsanzo shuga ndi glucose dehydrogenase).
➢ AmDH ayenera kuwonjezeredwa otsiriza mu anachita dongosolo, pambuyo pH ndi kutentha kusinthidwa kuti chikhalidwe.
Chitsanzo 1 (Kaphatikizidwe ka ma chiral amines ndi reductive amination alkyl aryl ketones)(1):
Sungani zaka 2 pansi -20 ℃.
Osakhudzana ndi zinthu zowopsa monga: kutentha kwambiri, kutsika / kutsika pH komanso zosungunulira za organic.
1. Kong W, Liu Y, Huang C, et al.Angewandte Chemie International Edition, 2022: e202202264.
