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Ma Oxynitrilase (HNL)
Zokhudza ma oxynitrilase
ES-HNLs: Enzyme ya gulu lomwe limapangitsa kuti HCN iwonjezeredwe ku aldehydes (ketones) kuti ipange ma cyanide alcohols amtundu wa R kapena S, omwe amatha kusinthidwa mosavuta kukhala mitundu yambiri ya mankhwala kapena mankhwala ophatikizana pogwiritsa ntchito njira ya mankhwala.
Pali mitundu 29 ya zinthu zopangidwa ndi oxynitrilase (Nambala monga ES-HNL-101 ~ ES-HNL-129) zomwe zapangidwa ndi SyncoZymes. SZ-HNL ndi chida chothandiza popanga (R)-cyanohydrins kapena (S)-cyanohydrins kuchokera ku mitundu yosiyanasiyana ya aldehydes kapena ma ketones a aromatic, aliphatic ndi heterocyclic.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Nitro reductase (NTR)
Zokhudza nitro reductase
ES-NTRs: Ndi ma flavoenzymes omwe amayambitsa kuchepa kwa magulu a nitro omwe amadalira NAD(P)H pa nitroaromatic ndi nitroheterocyclic compounds kukhala hydroxylamino ndi/kapena amino derivatives. Amagwiritsidwa ntchito kwambiri popanga organic aromatic hydroxylamine ndi aromatic amine, chithandizo cha chotupa, kuzindikira zamoyo komanso kuwonongeka kwa zinthu zodetsa chilengedwe. Pali mitundu 12 ya zinthu za Nitro reductase (NTR) (Nambala monga ES-NTR-101~ES-NTR-112) zopangidwa ndi SyncoZymes.
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Aldolase (DERA)
ES-DERA: Zingathe kuyambitsa bwino kuwonjezera kwa ma ketone a donor ku ma receptor aldehydes. Komanso, izi zitha kuchitika mu njira yamadzi ya pH yopanda mpweya popanda njira zapadera zodzitetezera. Zili m'gulu la aldolase la kalasi I, lomwe limapanga maziko a Shiff mu njira yopangira mphamvu. Gawoli limalumikizidwa pamodzi ndi gulu la amino la malo ogwirira ntchito kuti liyambe kusweka ndi kupanga mgwirizano. Kusiyana pakati pa ma DERA ndi ma aldolase ena ndikuti magawo omwe amapangira mphamvu ndi aldehydes ndipo amatha kuzizira mosalekeza.
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Cytochrome P450 monooxygenase (CYP)
Zokhudza CYP
ES-CYPs: Gulu la ma enzyme a redox omwe ali ndi mercaptan-heme ngati malo ogwirira ntchito poyambitsa kusamutsa mpweya. Ndi ma terminal oxygenases ndipo amafunika heme kuti ayambitse mpweya.
Cytochrome P450 monooxygenase imayambitsa okosijeni, epoxidation ndi hydroxylation ya alkyl, hydroxylation ndi okosijeni ya ammonia, okosijeni ya sulfure, dealkylation (oxygen, sulfure, ammonia), okosijeni dehydrogenation, deamination ndi dehalogenation.
Pali mitundu 8 ya zinthu za cytochrome P450 monooxygenase (Nambala monga ES-CYP-101～ES-CYP-108) zopangidwa ndi SyncoZymes.Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Mowa wochuluka (AOX)
Zokhudza mowa oxidase
ES-AOXs: Ma enzyme amenewa amatha kuyambitsa okosijeni wa mafuta ochulukirapo kapena aryl-alcohols kuti apange aldehydes. Amagwiritsa ntchito okosijeni wa mamolekyu koma safuna cofactor yowonjezerapo, ndi hydrogen peroxide yopangidwa.
Pali mitundu 6 ya zinthu zopangidwa ndi mowa (Nambala monga ES-AOX-101~ES-AOX-106) zomwe zapangidwa ndi SyncoZymes. ES-AOX101 ndi ES-AOX102 amakonda zinthu zopangidwa ndi mowa wa aliphatic, ES-AOX103~ ES-AOX105 amakonda zinthu zopangidwa ndi mowa wa aromatic, ndipo ES-AOX106 ndi cholesterol oxidase. SZ-AOX ndi chida chothandiza chothandizira kusungunuka kwa mafuta a alcohols kapena aryl-alcohols kuti apange aldehydes.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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D-Amino acid dehydrogenase (D-AADH)
Zokhudza D-Amino acid dehydrogenase
ES-D-AADH (D-Amino acid dehydrogenase): enzyme yomwe imatha kuchepetsa 2-keto acid kukhala D-amino acid yofanana. Zomwe zimachitika zimafuna NADP(H) ndi inorganic ammonia donor (monga ammonia kapena ammonium ion). Pali mitundu 17 ya D-amino acid dehydrogenases (Nambala monga ES-DAADH-101~ ES-DAADH-117) yopangidwa ndi SyncoZymes.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Esterase ndi Lipase (PLE ndi CALB)
Zokhudza Esterase & Lipase
ES-PLEs: Gulu la ma hydrolases omwe amalimbikitsa kupangika ndi kusweka kwa ma ester bond. Amatha kutenga nawo mbali pamitundu yosiyanasiyana ya zochita za biochemical, monga esterification, transesterification ndi hydrolysis. Amagwiritsidwa ntchito kwambiri m'magawo ambiri monga kukonza chakudya, makampani opanga mankhwala, biomedicine, mankhwala a chiral ndi chithandizo cha chilengedwe.
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Epoxide hydrolase (EH)
Zokhudza epoxide hydrolase
EH ndi ether hydrolase yomwe imayambitsa hydrolysis ya stereoselective ya racemic epoxides kuti ipange 1, 2-diol ndi optically active epoxides, zomwe zingagwiritsidwe ntchito pokonza chiral ya epoxides kapena kukonzekera chiral diols. Amagwiritsidwa ntchito kwambiri mu zamankhwala ndi madera ena. Pali mitundu itatu ya epoxide hydrolases products (Nambala monga ES-EH-101 ~ ES-EH-103) yopangidwa ndi SyncoZymes. ES-EH ndi chida chothandiza chothandizira kupanga chiral alcohols kudzera mu stereoselective hydrolysis ya aliphatic ndi aromatic epoxides.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Formate dehydrogenase (FDH)
Zokhudza Formate dehydrogenase
ES-FDH (Formate dehydrogenase): FDH imayambitsa kuchepa kwa hydrogenation ya ammonium formate kuti ipange carbon dioxide ndi ammonia, ndikuchepetsa NAD kukhala NADH ndi NAD ngati cholandirira ma electron. FDH nthawi zambiri imagwiritsidwa ntchito pokonzanso coenzyme NADH. Pali mitundu inayi ya zinthu za FDH enzyme (ES-FDH-101~ES-FDH-104) zomwe zimapangidwa ndi SyncoZymes, zomwe ES-FDH102 imakhala ndi ntchito yayikulu kwambiri ndipo ndiyo FDH yomwe ikulimbikitsidwa kwambiri.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Glucose dehydrogenase (GDH)
Zokhudza Glucose dehydrogenase
ES-GDH (Glucose dehydrogenase): GDH imayambitsa kuchepa kwa glucose kuti ipange gluconic acid (lactone), ndikuchepetsa NAD(P)+ kukhala NAD(P)H, ndi NAD(P)+ ngati cholandirira ma elekitironi. GDH nthawi zambiri imagwiritsidwa ntchito pokonzanso coenzyme NAD(P)H m'magawo a biocatalysis ndi ma enzyme ena akuluakulu. Pali mitundu 10 ya zinthu za GDH enzyme (ES-GDH-101~ES-GDH-110) zopangidwa ndi SyncoZymes, zomwe ES-GDH110 imakhala ndi ntchito yayikulu kwambiri ndipo ndiyo GDH yomwe ikulimbikitsidwa kwambiri.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Monoamine oxidase (MAO)
Zokhudza Monoamine oxidase
ES-MAO (Monoamine oxidase): MAO imayambitsa kuchotsedwa kwa okosijeni kwa monoamines kuti ipange hydrogen peroxide, ammonia ndi ma aldehydes ofanana nawo. Mu njira yopangira okosijeni, mpweya umafunika ngati okosijeni. Pali mitundu 6 ya zinthu za MAO enzyme (Nambala monga ES-MAO-101 ~ ES-MAO-106) yopangidwa ndi SyncoZymes, yomwe ingagwiritsidwe ntchito pochotsa okosijeni kwa mankhwala a monoamine.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Lactate Dehydrogenase (LDH)
Zokhudza Lactate dehydrogenase
Pali mtundu umodzi wa LDH enzyme product (Nambala monga ES-LDH) yopangidwa ndi SyncoZymes. LDH imatha kuyambitsa kuchepa kwa pyruvate kukhala L-lactic acid, kapena kuchepetsa ma α-keto acid ena ofanana. Mu catalysis, NADH ndi yofunika ngati chonyamulira hydrogen.
Lactate dehydrogenase mtundu wa catalytic reaction
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
