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D-Amino acid dehydrogenase (D-AADH)
Zokhudza D-Amino acid dehydrogenase
ES-D-AADH (D-Amino acid dehydrogenase): enzyme yomwe imatha kuchepetsa 2-keto acid kukhala D-amino acid yofanana. Zomwe zimachitika zimafuna NADP(H) ndi inorganic ammonia donor (monga ammonia kapena ammonium ion). Pali mitundu 17 ya D-amino acid dehydrogenases (Nambala monga ES-DAADH-101~ ES-DAADH-117) yopangidwa ndi SyncoZymes.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Esterase ndi Lipase (PLE ndi CALB)
Zokhudza Esterase & Lipase
ES-PLEs: Gulu la ma hydrolases omwe amalimbikitsa kupangika ndi kusweka kwa ma ester bond. Amatha kutenga nawo mbali pamitundu yosiyanasiyana ya zochita za biochemical, monga esterification, transesterification ndi hydrolysis. Amagwiritsidwa ntchito kwambiri m'magawo ambiri monga kukonza chakudya, makampani opanga mankhwala, biomedicine, mankhwala a chiral ndi chithandizo cha chilengedwe.
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Epoxide hydrolase (EH)
Zokhudza epoxide hydrolase
EH ndi ether hydrolase yomwe imayambitsa hydrolysis ya stereoselective ya racemic epoxides kuti ipange 1, 2-diol ndi optically active epoxides, zomwe zingagwiritsidwe ntchito pokonza chiral ya epoxides kapena kukonzekera chiral diols. Amagwiritsidwa ntchito kwambiri mu zamankhwala ndi madera ena. Pali mitundu itatu ya epoxide hydrolases products (Nambala monga ES-EH-101 ~ ES-EH-103) yopangidwa ndi SyncoZymes. ES-EH ndi chida chothandiza chothandizira kupanga chiral alcohols kudzera mu stereoselective hydrolysis ya aliphatic ndi aromatic epoxides.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Formate dehydrogenase (FDH)
Zokhudza Formate dehydrogenase
ES-FDH (Formate dehydrogenase): FDH imayambitsa kuchepa kwa hydrogenation ya ammonium formate kuti ipange carbon dioxide ndi ammonia, ndikuchepetsa NAD kukhala NADH ndi NAD ngati cholandirira ma electron. FDH nthawi zambiri imagwiritsidwa ntchito pokonzanso coenzyme NADH. Pali mitundu inayi ya zinthu za FDH enzyme (ES-FDH-101~ES-FDH-104) zomwe zimapangidwa ndi SyncoZymes, zomwe ES-FDH102 imakhala ndi ntchito yayikulu kwambiri ndipo ndiyo FDH yomwe ikulimbikitsidwa kwambiri.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Glucose dehydrogenase (GDH)
Zokhudza Glucose dehydrogenase
ES-GDH (Glucose dehydrogenase): GDH imayambitsa kuchepa kwa glucose kuti ipange gluconic acid (lactone), ndikuchepetsa NAD(P)+ kukhala NAD(P)H, ndi NAD(P)+ ngati cholandirira ma elekitironi. GDH nthawi zambiri imagwiritsidwa ntchito pokonzanso coenzyme NAD(P)H m'magawo a biocatalysis ndi ma enzyme ena akuluakulu. Pali mitundu 10 ya zinthu za GDH enzyme (ES-GDH-101~ES-GDH-110) zopangidwa ndi SyncoZymes, zomwe ES-GDH110 imakhala ndi ntchito yayikulu kwambiri ndipo ndiyo GDH yomwe ikulimbikitsidwa kwambiri.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Monoamine oxidase (MAO)
Zokhudza Monoamine oxidase
ES-MAO (Monoamine oxidase): MAO imayambitsa kuchotsedwa kwa okosijeni kwa monoamines kuti ipange hydrogen peroxide, ammonia ndi ma aldehydes ofanana nawo. Mu njira yopangira okosijeni, mpweya umafunika ngati okosijeni. Pali mitundu 6 ya zinthu za MAO enzyme (Nambala monga ES-MAO-101 ~ ES-MAO-106) yopangidwa ndi SyncoZymes, yomwe ingagwiritsidwe ntchito pochotsa okosijeni kwa mankhwala a monoamine.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Lactate Dehydrogenase (LDH)
Zokhudza Lactate dehydrogenase
Pali mtundu umodzi wa LDH enzyme product (Nambala monga ES-LDH) yopangidwa ndi SyncoZymes. LDH imatha kuyambitsa kuchepa kwa pyruvate kukhala L-lactic acid, kapena kuchepetsa ma α-keto acid ena ofanana. Mu catalysis, NADH ndi yofunika ngati chonyamulira hydrogen.
Lactate dehydrogenase mtundu wa catalytic reaction
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Imine reductase (IRED)
About Ine reductase
ES-IRED: Gulu la ma enzyme omwe amalimbikitsa kuchepetsa kwa C=N bond ku CN bond. Ndi la redox enzyme, yokhala ndi coenzyme NADPH yoyendetsera hydrogen. Malinga ndi zomwe chiral amakonda, amatha kugawidwa m'magulu a R-IRED ndi S-IRED. Syncozymes adapanga ma imine reductase 15 (numbIRED ES-IRED-101-ES-IRED-115), omwe angagwiritsidwe ntchito kwambiri pochepetsa regioselective ndi stereoselective ya imines kuti akonze ma chiral amines.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Nitrile reductase (NRED)
Zokhudza Nitrile reductase
Pali mitundu itatu ya mankhwala a NRED enzyme (Nambala monga ES-NRED101~ ES-NRED103) yopangidwa ndi SyncoZymes. NRED imatha kuyambitsa kuchepa kwa gulu la nitrile kukhala amine. Mu catalysis, NADPH imafunika ngati chonyamulira hydrogen.
Nitrile reductasecatalytic reaction mtundu
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Leucine Dehydrogenase (LeuDH)
Zokhudza Leucine dehydrogenase
Pali mtundu umodzi wa mankhwala a enzyme a LeuDH (Nambala monga ES-LeuDH-101) omwe adapangidwa ndi SyncoZymes. LeuDH imatha kuyambitsa ammoniation yochepetsa mphamvu ya 4-methylbutanoic acid (mchere) kupita ku L-leucine kapena okosijeni ya leucine kupita ku 4-methylbutanoic acid. ES-LeuDH imathanso kuyambitsa mphamvu yochepetsa mphamvu ya α-keto acids yokhala ndi kapangidwe kofanana kuti ikonzekere zotumphukira za amino acid zofanana. Mu njira ya catalysis, NADH ndiyofunikira ngati chonyamulira hydrogen.
Leucine dehydrogenase mtundu wa catalytic reaction
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Threonine deaminase (TDA)
About Threonine deaminase
ES-TDA (Threonine deaminase): puloteni ya pyridoxal phosphate yomwe imayambitsa kuchotsedwa kwa threonine kuti ipange 2-ketobutyric acid ndi ammonia. Pyridoxal 5-phosphate ndi yofunika ngati coenzyme mu dongosolo lothandizira. Pali mtundu umodzi wokha wa mankhwala a TDA enzyme (Nambala monga ES-TDA) yopangidwa ndi SyncoZymes, yomwe ingagwiritsidwe ntchito kukonzekera 2-ketobutyric acid kapena zotumphukira zake kuchokera ku threonine.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Amine Dehydrogenase (AmDH)
Zokhudza Amine Dehydrogenase
ES-AmDH (Amine Dehydrogenase): enzyme yomwe ingathandize kupanga ammoniation ya gulu la carbonyl ndikulichepetsa kukhala gulu la amino. Ndi enzyme yodalira coenzyme NADH, ndipo NADH imagwira ntchito ngati chotumizira hydrogen. Pali mitundu inayi ya zinthu za enzyme ya AmDH (Nambala monga ES-AmDH101 ~ ES-AmDH104) yopangidwa ndi SyncoZymes, yomwe ingagwiritsidwe ntchito mu regioselective kapena stereoselective reductive amination ya aldehydes ndi ketones.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
