SyncoZymes

mankhwala

Imine reductase (IRED)

Kufotokozera Kwachidule:

Za Imine reductase

ES-IRED: Gulu la michere yomwe imathandizira kuchepetsa C=N chomangira ku CN chomangira.Ndi ya redox enzyme, yokhala ndi coenzyme NADPH yoyendetsa ma hydrogen.Malinga ndi zokonda zachiral za zinthuzo, zitha kugawidwa kukhala R-IRED ndi S-IRED.Ma syncozymes adapanga 15 imine reductases (nambala ES-IRED-101-ES-IRED-115), yomwe ingagwiritsidwe ntchito kwambiri pochepetsa regioselective ndi stereoselective ya imines kukonzekera ma chiral amines.
Mtundu wa Catalytic reaction:

Imine reductase (IRED)2

Mobile/Wechat/WhatsApp: +86-13681683526

Imelo:lchen@syncozymes.com


Tsatanetsatane wa Zamalonda

Zogulitsa Tags

Zambiri Zamalonda:

Imine reductase (IRED)
Ma enzyme Kodi katundu Kufotokozera
Enzyme Powder ES-IRED-101~ ES-IRED-114 seti ya 14 Imine Reductase, 50 mg iliyonse
96-Chabwino Enzyme Screening Kit ES-IRED-1400 seti ya 14 Imine Reductase, 1 mg iliyonse

Ubwino:

★ Kukhazikika kwa gawo lapansi.
★ Kusankha kwamphamvu kwachiral.
★ Kutembenuka kwakukulu.
★ Zogulitsa zochepa.
★ Mkhalidwe wofatsa.
★ Okonda zachilengedwe.

Malangizo ogwiritsira ntchito:

➢ Nthawi zambiri, kachitidwe kachitidwe kamayenera kukhala ndi gawo lapansi, yankho la buffer, enzyme, coenzyme, ndi coenzyme regeneration system.
➢ Mitundu yonse ya ma ES-IREDs ofanana ndi momwe zinthu zilili bwino ziyenera kuwerengedwa payekhapayekha.
➢ Malo okhala ndi zinthu zambiri kapena zinthu zomwe zili nazo zitha kulepheretsa ES-IRED kugwira ntchito.Komabe, zoletsazo zitha kumasulidwa ndikuwonjezera batch ya gawo lapansi.

Zitsanzo za Ntchito:

Chitsanzo 1(Biosynthesis of chiral 2-methyl pyrrolidine)(1):

Imine reductase (IRED)3

Chitsanzo 2(Biosynthesis of secondary amine)(2):

Imine reductase (IRED)4

Chitsanzo 3 (Kuchepetsa kwa Cyclic Imines)(3):

Imine reductase (IRED)5

Posungira:

Sungani zaka 2 pansi -20 ℃.

Chenjerani:

Osakhudzana ndi zinthu zowopsa monga: kutentha kwambiri, kutsika / kutsika pH komanso zosungunulira za organic.

Zolozera:

1. Scheller PN, Fademrecht S, Hofelzer S, et al.ChemBioChem, 2014, 15, 2201-2204.
2. Wetzl D, Gand M, Ross A, et al.ChemCatChem, 2016, 8, 2023-2026.
3. Li H, Luan ZJ, Zheng GW, et al.Adv.Synth.Catal.2015, 357, 1692-1696.


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