Epoxide hydrolase (EH)

Kufotokozera Kwachidule:

Zokhudza epoxide hydrolase

EH ndi ether hydrolase yomwe imayambitsa hydrolysis ya stereoselective ya racemic epoxides kuti ipange 1, 2-diol ndi optically active epoxides, zomwe zingagwiritsidwe ntchito pokonza chiral ya epoxides kapena kukonzekera chiral diols. Amagwiritsidwa ntchito kwambiri mu zamankhwala ndi madera ena. Pali mitundu itatu ya epoxide hydrolases products (Nambala monga ES-EH-101 ~ ES-EH-103) yopangidwa ndi SyncoZymes. ES-EH ndi chida chothandiza chothandizira kupanga chiral alcohols kudzera mu stereoselective hydrolysis ya aliphatic ndi aromatic epoxides.

Mtundu wa catalytic reaction:

Epoxide hydrolase EH2

Foni yam'manja/Wechat/WhatsApp: +86-13681683526

Imelo:lchen@syncozymes.com

Tumizani imelo kwa ife

Tsatanetsatane wa Zamalonda

Ma tag a Zamalonda

Zambiri Zamalonda:

Ma enzyme	Khodi ya Zamalonda	Kufotokozera
Ufa wa Enzyme	ES-EH-101~ ES-EH-103	seti ya Epoxide Hydrolases zitatu, 50 mg iliyonse Zinthu zitatu * 50mg / chinthu, kapena kuchuluka kwina
Zida Zowunikira (SynKit)	ES-EH-300	seti ya ma Epoxide Hydrolases atatu, 1 mg iliyonse Zinthu zitatu * 1mg / chinthu

Ubwino:

★ Kuchuluka kwa substrate.
★ Kusankha bwino kwa chiral.
★ Kusintha kwakukulu.
★ Zogulitsa zochepa.
★ Zinthu zofatsa zomwe zimachitika chifukwa cha kukwiya.
★ Yosamalira chilengedwe.

Malangizo ogwiritsira ntchito:

Kawirikawiri, njira yochitira zinthu iyenera kukhala ndi substrate, yankho la buffer (pH yabwino kwambiri) ndi ES-EH.
➢ Mitundu yonse ya ES-EHs yogwirizana ndi machitidwe osiyanasiyana abwino kwambiri iyenera kuphunziridwa payekhapayekha.
➢ Kuchuluka kwa zinthu zomwe zili ndi substrate kapena mankhwala ena kungalepheretse ntchito ya ES-EH. Komabe, kuletsa kumeneku kungachepetsedwe powonjezera substrate.