Transaldolase (TAL)
Kufotokozera Kwachidule:
Zokhudza Transaldolase
ES-TAL (Transaldolase): makamaka imatanthauza ma transaldolase a threonine, omwe amatha kuyambitsa zomwe zimachitika popanga ma derivatives a β-hydroxyphenylalanine ndi ma derivatives a threonine ndi benzaldehyde. TAL ndi enzyme yodalira PLP. Pali mtundu umodzi wokha wa mankhwala a enzyme ya TAL (Nambala monga ES-TAL101) yopangidwa ndi SyncoZymes, yomwe ingagwiritsidwe ntchito popanga β-hydroxyphenylalanine ndi ma derivatives ake.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
★ Kuchuluka kwa substrate.
★ Kusankha bwino kwa chiral.
★ Kusintha kwakukulu.
★ Zogulitsa zochepa.
★ Zinthu zofatsa zomwe zimachitika chifukwa cha kukwiya.
★ Yosamalira chilengedwe.
➢ Kawirikawiri, dongosolo la reaction liyenera kukhala ndi substrate, buffer solution, enzyme, PLP, Mg2+.
➢ TAL iyenera kuwonjezeredwa komaliza mu dongosolo la reaction, pH ndi kutentha zitasinthidwa kuti zigwirizane ndi momwe reaction ilili.
Chitsanzo 1 (Kupangidwa kwa (2S, 3R)-p-methylsulfonyl phenylserine kuchokera ku p-methylsulfonyl benzaldehyde ndi threonine)(1):
Sungani kwa zaka ziwiri pansi pa -20℃.
Musagwirizane ndi zinthu zoopsa monga: kutentha kwambiri, pH yapamwamba/yotsika komanso organic solvent yochuluka.
1. CN109836362B
