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Nucloside phosphorylse (NP)
About nucleoside phosphorylse
Pali mitundu itatu ya zinthu zopangidwa ndi enzyme ya NP (Nambala monga ES-NP-101~ ES-NP-103) zomwe zapangidwa ndi SyncoZymes. ES-NP-101 ndi purine nucleoside phosphorylase, ES-NP-102 ndi ES-NP-103 ndi pyrimidine nucleoside phosphorylase. Nucleosidephosphorylase imatha kuwononga ma nucleosides kukhala maziko ndi pentose phosphate. Nucleoside phosphorylase ikhoza kugawidwa m'magulu awiri: purine nucleoside phosphorylase ndi pyrimidine nucleoside phosphorylase malinga ndi zomwe ma nucleoside bases amakonda. Purine nucleoside phosphorylase imatha kusintha adenosine kukhala adenine, inosine kukhala hypoxanthine, guanosine kukhala guanine, ndikupanga ribose phosphate nthawi imodzi. Pyrimidine nucleoside phosphorylase imatha kusintha uridine kukhala uracil ndikupanga ribose phosphate.
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Imelo:lchen@syncozymes.com
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Hydroaminase (HAM)
Zokhudza Hydroaminase
Pali mitundu iwiri ya mankhwala a HAM enzyme (Nambala monga ES-HAM-101~ ES-HAM-102) yopangidwa ndi SyncoZymes. HAM imatha kuyambitsa ammonia ya enoic acid kapena zotumphukira zake kuti ipange chiral amino acid. HAM ingagwiritsidwe ntchito kupanga chiral amino acid (kapena chiral amines) kuchokera ku enoic acids (kapena alkenes). Wopereka ammonia, monga madzi a ammonia kapena mchere wa ammonium, ndi wofunikira.
Hydroaminase catalytic reaction mtundu
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Imelo:lchen@syncozymes.com
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CALB Yosayenda
CALB
Lipase B yopangidwanso kuchokera ku Candida antarctica (CALB) imapangidwa pogwiritsa ntchito kuwiritsa pansi pa madzi pogwiritsa ntchito Pichia pastoris yosinthidwa majini.
CALB ingagwiritsidwe ntchito mu gawo la madzi kapena gawo lachilengedwe lothandizira esterification, esterolysis, transesterification, ring opening polyester synthesis, aminolysis, hydrolysis of amides, acylation of amines ndi addition reaction.
CALB ili ndi kusankha kwakukulu kwa chiral komanso kusankha malo, kotero ingagwiritsidwe ntchito kwambiri mu kukonza mafuta, chakudya, mankhwala, zodzoladzola ndi mafakitale ena a mankhwala.
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Imelo:lchen@syncozymes.com
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NADH oxidase (NOX)
Zokhudza NADH oxidase
ES-NOX (NADH oxidase): NOX imayambitsa okosijeni wa NADH kukhala NAD+, ndipo ndi ya oxidoreductase. Mu ndondomeko ya okosijeni, O2 ndi yofunika ngati okosijeni, ndipo imachepetsedwa kukhala H2O kapena H2O2. Pali mitundu inayi ya zinthu za NOX enzyme (ES-NOX-101~ES-NOX-104) zomwe zapangidwa ndi kampani yathu, zomwe zingagwiritsidwe ntchito pokonzanso okosijeni wa coenzyme NAD+.
Mtundu wa catalytic reaction:
or
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Imelo:lchen@syncozymes.com
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Phenylalanine ammonia lyase (PAL)
About Phenylalanine ammonia lyase
ES-PAL: Gulu la ma enzyme omwe amachititsa kuti L-phenylalanine ichotsedwe mwachindunji kukhala transcinnamic acid. Syncozymes adapanga zinthu 10 za phenylalanine ammonia lyase (yolembedwa ndi manambala a ES-PAL-101~ES-PAL-110), zomwe zingagwiritsidwe ntchito pochotsa kapena kubwezera phenylalanine ndi zotumphukira zake.
Mtundu wa catalytic reaction:
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Imelo:lchen@syncozymes.com
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Katalase (CAT)
Zokhudza Catalase
ES-CAT (Catalase): imayambitsa kuwonongeka kwa H2O2 kukhala mpweya ndi madzi. Imapezeka makamaka mu mitochondria, endoplasmic reticulum, chiwindi cha nyama ndi maselo ofiira a magazi, makamaka m'chiwindi chomwe chili ndi kuchuluka kwakukulu, zomwe zimapangitsa kuti thupi liziteteza ku ma antioxidants. Mu biocatalysis, imagwiritsidwa ntchito kwambiri kuchotsa hydrogen peroxide yomwe imachokera ku reaction ndikuchepetsa kuletsa ndi kuletsa kwa enzyme ndi hydrogen peroxide. Pali mtundu umodzi wokha wa zinthu za enzyme za CAT zomwe zimapangidwa ndi SyncoZymes (Nambala monga ES-CAT).
Mtundu wa catalytic reaction:
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Imelo:lchen@syncozymes.com
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Lysine oxidase (LO)
Zokhudza Lysine oxidase
ES-LO (Lysine oxidase): imayambitsa okosijeni wa L-lysine kukhala 6-amino-2-oxohexanoic acid (kapena lactone yake). Pali mtundu umodzi wokha wa LO enzyme product (Nambala monga ES-LO) yopangidwa ndi SyncoZymes.
Mtundu wa catalytic reaction:
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Imelo:lchen@syncozymes.com
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Phosphokinase (PKase)
Zokhudza Phosphokinase
ES-PKase (Phosphokinase): imayambitsa kusamutsa magulu a phosphate pa ATP kupita ku mankhwala ena. Imalimbikitsanso kusamutsa magulu a phosphate pa ma nucleoside ena a triphosphate nthawi zina. Ma kinase ambiri amafunika ma ayoni achitsulo osakanikirana kuti agwire nawo ntchito (nthawi zambiri Mg2+). Pali mitundu 21 ya zinthu za PKase enzyme (Nambala monga ES-PKase101~ ES-PKase-121) zopangidwa ndi SyncoZymes.
Mtundu wa catalytic reaction:
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Imelo:lchen@syncozymes.com
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Cyclooxygenase (COX)
Zokhudza Cyclooxygenase
ES-COX (Cyclooxygenase): imayambitsa kusintha kwa ma bond a C=C kukhala epoxide. Pali mitundu 11 ya zinthu za COX enzyme (Nambala monga ES-COX101~ ES-COX-111) zomwe zimapangidwa ndi SyncoZymes. Malinga ndi njira zosiyanasiyana zoyendetsera, COX ya SyncoZymes imagawidwa mu haloperoxidase ndi styrene monooxygenase. ES-COX101, 102, 107-111 ndi ya haloperoxidase, pomwe ES-COX103-106 ndi ya styrene monooxygenase.
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Imelo:lchen@syncozymes.com
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Cyclohexanone monooxygenase (CHMO)
Zokhudza Cyclohexanone monooxygenase
ES-CHMO (Cyclohexanone monooxygenase): Baeyer Villiger monooxygenase (BVMO) yokhala ndi cyclohexanone ngati substrate, imatha kupangitsa cyclohexanone kukhala cyclohexanol pogwiritsa ntchito mpweya.
Ndi mtundu wa enzyme yomwe imadalira flavin. Flavin yosungunuka imachepetsedwa kukhala flavin kudzera mu kayendedwe ka kuchepetsa coenzyme II (NADPH) kuti iwonongeke. Chifukwa chake, cofactor NADPH ndiyofunikira mu kayendedwe ka flavin. Pali mtundu umodzi wokha wa enzyme ya CHMO (Nambala monga ES-CHMO101) yomwe idapangidwa ndi SyncoZymes, yomwe ingagwiritsidwe ntchito kupangitsa cyclohexanone kukhala cyclohexanone.
Mtundu wa catalytic reaction:
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Imelo:lchen@syncozymes.com
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Carboxylic acid reductase (CAR)
Zokhudza Carboxylic acid reductase
ES-CAR (Carboxylic acid reductase): imayambitsa kuchepetsa gulu la carboxyl kukhala gulu la aldehyde. Mu njira yothandiza, kuyambitsa ATP ndi coenzyme NADPH ndizofunikira ngati zonyamula hydrogen. Pali mitundu iwiri ya zinthu za CAR enzyme (Nambala monga ES-CAR101~ ES-CAR-102) zopangidwa ndi SyncoZymes.
Mtundu wa catalytic reaction:
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Imelo:lchen@syncozymes.com
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Phenylalanine dehydrogenase (PDH)
About Phenylalanine dehydrogenase
ES-PDH: Gulu la oxidoreductase. Yankho labwino likhoza kuyambitsa kuchotsedwa kwa okosijeni kwa mchere wa L phenylalanine pamaso pa NAD kuti apange mchere wa phenylpyruvate, ndipo yankho lotsutsana nalo likhoza kuyambitsa kupanga mchere wa amino acid wofanana kuchokera ku mchere wa phenylpyruvate. Syncozymes adapanga zinthu 8 za phenylalanine dehydrogenase (yolembedwa ndi manambala a ES-PDH-101~ES-PDH-108). ES-PDH ingagwiritsidwe ntchito kukonza mchere wa phenylalanine kapena mchere wa amino acid wofanana kuchokera ku mchere wa phenylpyruvic acid kapena zotumphukira.
Mtundu wa catalytic reaction:
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Imelo:lchen@syncozymes.com
