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Transaldolase (TAL)
Zokhudza Transaldolase
ES-TAL (Transaldolase): makamaka imatanthauza ma transaldolase a threonine, omwe amatha kuyambitsa zomwe zimachitika popanga ma derivatives a β-hydroxyphenylalanine ndi ma derivatives a threonine ndi benzaldehyde. TAL ndi enzyme yodalira PLP. Pali mtundu umodzi wokha wa mankhwala a enzyme ya TAL (Nambala monga ES-TAL101) yopangidwa ndi SyncoZymes, yomwe ingagwiritsidwe ntchito popanga β-hydroxyphenylalanine ndi ma derivatives ake.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Ketoreductase (KRED)
Zokhudza Ketoreductase
Ma enzyme: Ndi ma macromolecular biological catalysts, ma enzyme ambiri ndi mapuloteni.
Ketoreductase: Amatchedwanso "Carbonyl reductase", ndi ma enzyme omwe amachititsa kuti reversible redox reaction pakati pa aldehydes / ketones ndi alcohols zichitike, ndipo amafunika ma coenzymes ngati H transmitter monga NADH kapena NADPH. Pali magulu atatu akuluakulu a KRED: Short-chain Dehydrogenase / Reductases (SDRs), Medium-chain Dehydrogenases / Reductases (MDRs), ndi Aldo-KetoReductases (AKRs). Ntchito zoyambitsa za zitatuzi ndizofanana, koma kapangidwe ndi makhalidwe ake ndi osiyana kwambiri.
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Transaminase (ATA)
Zokhudza transaminase
ATA yochokera ku SyncoZymes: Pali mitundu 66 ya zinthu za enzyme ya ATA (Nambala monga ES-ATA-101~ES-ATA-166) yopangidwa ndi SyncoZymes. SZ-ATA ndi chida chothandiza chothandizira kupanga ma chiral amines, ma amino acid ndi zinthu zina zochokera ku ma aliphatic ndi aromatic keto acids, aldehydes, ma ketones ndi ma ketoses osiyanasiyana.
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Nitrilase (NIT)
About Nitrilase
ES-NITs: Sinthani mwachindunji gulu la cyanide kukhala gulu la carboxyl, kuti mukonzekere carboxylic acid, yomwe imagwiritsidwa ntchito kwambiri mu zamankhwala, kuteteza chilengedwe, makampani opanga mankhwala, zowonjezera chakudya, nsalu, ulimi ndi zina.
Pali mitundu 40 ya zinthu za Nitrilase (NIT) (Nambala monga ES-NIT-101~ES-NIT-140) yopangidwa ndi SyncoZymes. ES-NIT ndi chida chothandiza chothandizira kupanga chiral carboxylic acids kudzera mu regio- ndi stereoselective hydrolysis ya mitundu yosiyanasiyana ya aliphatic ndi aromatic nitriles.Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Nitrile hydratase (NHT)
Zokhudza ES-NHTs
ES-NHTs: gulu la metalloenzyme, lomwe limasankha ma nitriles kukhala ma primary amide ofanana. Amagwiritsidwa ntchito kwambiri osati kokha popanga ma amino acid, ma amide, ma carboxylic acid ndi zotumphukira zawo, komanso pokonzekera mankhwala a chiral. Pali mitundu 24 ya nitrile hydratases yomwe idapangidwa ndi SyncoZymes (Nambala monga ES-NHT-101 ~ ES-NHT-124).
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Amidase (AMD)
AMD kuchokera ku SyncoZymes: Pali mitundu 19 ya zinthu za enzyme za AMD (Nambala monga ES-AMD-101~ES-AMD-119) yopangidwa ndi SyncoZymes. SZ-AMD ndi chida chothandiza chothandizira kupanga ma chiral carboxylic acids ndi ma derivatives awo kuchokera ku mitundu yosiyanasiyana ya aliphatic ndi aromatic amides.
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Ene reductase (ERED)
About ene reductase
ES-EREDs: Ili m'gulu la ma enzyme akale achikasu omwe amachepetsa C=C m'ma α, β-unsaturated compounds okhala ndi magulu otenga ma electron. Amagwiritsidwa ntchito kwambiri pophunzira za amino acid derivatives, bioactive substances, pharmaceutical intermediates, spice ndi chiral blocks.
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Ma Oxynitrilase (HNL)
Zokhudza ma oxynitrilase
ES-HNLs: Enzyme ya gulu lomwe limapangitsa kuti HCN iwonjezeredwe ku aldehydes (ketones) kuti ipange ma cyanide alcohols amtundu wa R kapena S, omwe amatha kusinthidwa mosavuta kukhala mitundu yambiri ya mankhwala kapena mankhwala ophatikizana pogwiritsa ntchito njira ya mankhwala.
Pali mitundu 29 ya zinthu zopangidwa ndi oxynitrilase (Nambala monga ES-HNL-101 ~ ES-HNL-129) zomwe zapangidwa ndi SyncoZymes. SZ-HNL ndi chida chothandiza popanga (R)-cyanohydrins kapena (S)-cyanohydrins kuchokera ku mitundu yosiyanasiyana ya aldehydes kapena ma ketones a aromatic, aliphatic ndi heterocyclic.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Nitro reductase (NTR)
Zokhudza nitro reductase
ES-NTRs: Ndi ma flavoenzymes omwe amayambitsa kuchepa kwa magulu a nitro omwe amadalira NAD(P)H pa nitroaromatic ndi nitroheterocyclic compounds kukhala hydroxylamino ndi/kapena amino derivatives. Amagwiritsidwa ntchito kwambiri popanga organic aromatic hydroxylamine ndi aromatic amine, chithandizo cha chotupa, kuzindikira zamoyo komanso kuwonongeka kwa zinthu zodetsa chilengedwe. Pali mitundu 12 ya zinthu za Nitro reductase (NTR) (Nambala monga ES-NTR-101~ES-NTR-112) zopangidwa ndi SyncoZymes.
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Aldolase (DERA)
ES-DERA: Zingathe kuyambitsa bwino kuwonjezera kwa ma ketone a donor ku ma receptor aldehydes. Komanso, izi zitha kuchitika mu njira yamadzi ya pH yopanda mpweya popanda njira zapadera zodzitetezera. Zili m'gulu la aldolase la kalasi I, lomwe limapanga maziko a Shiff mu njira yopangira mphamvu. Gawoli limalumikizidwa pamodzi ndi gulu la amino la malo ogwirira ntchito kuti liyambe kusweka ndi kupanga mgwirizano. Kusiyana pakati pa ma DERA ndi ma aldolase ena ndikuti magawo omwe amapangira mphamvu ndi aldehydes ndipo amatha kuzizira mosalekeza.
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Cytochrome P450 monooxygenase (CYP)
Zokhudza CYP
ES-CYPs: Gulu la ma enzyme a redox omwe ali ndi mercaptan-heme ngati malo ogwirira ntchito poyambitsa kusamutsa mpweya. Ndi ma terminal oxygenases ndipo amafunika heme kuti ayambitse mpweya.
Cytochrome P450 monooxygenase imayambitsa okosijeni, epoxidation ndi hydroxylation ya alkyl, hydroxylation ndi okosijeni ya ammonia, okosijeni ya sulfure, dealkylation (oxygen, sulfure, ammonia), okosijeni dehydrogenation, deamination ndi dehalogenation.
Pali mitundu 8 ya zinthu za cytochrome P450 monooxygenase (Nambala monga ES-CYP-101～ES-CYP-108) zopangidwa ndi SyncoZymes.Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
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Mowa wochuluka (AOX)
Zokhudza mowa oxidase
ES-AOXs: Ma enzyme amenewa amatha kuyambitsa okosijeni wa mafuta ochulukirapo kapena aryl-alcohols kuti apange aldehydes. Amagwiritsa ntchito okosijeni wa mamolekyu koma safuna cofactor yowonjezerapo, ndi hydrogen peroxide yopangidwa.
Pali mitundu 6 ya zinthu zopangidwa ndi mowa (Nambala monga ES-AOX-101~ES-AOX-106) zomwe zapangidwa ndi SyncoZymes. ES-AOX101 ndi ES-AOX102 amakonda zinthu zopangidwa ndi mowa wa aliphatic, ES-AOX103~ ES-AOX105 amakonda zinthu zopangidwa ndi mowa wa aromatic, ndipo ES-AOX106 ndi cholesterol oxidase. SZ-AOX ndi chida chothandiza chothandizira kusungunuka kwa mafuta a alcohols kapena aryl-alcohols kuti apange aldehydes.
Mtundu wa catalytic reaction:
Foni yam'manja/Wechat/WhatsApp: +86-13681683526
Imelo:lchen@syncozymes.com
