Aldolase (DERA)

Kufotokozera Kwachidule:

ES-DERA: Zingathe kuyambitsa bwino kuwonjezera kwa ma ketone a donor ku ma receptor aldehydes. Komanso, izi zitha kuchitika mu njira yamadzi ya pH yopanda mpweya popanda njira zapadera zodzitetezera. Zili m'gulu la aldolase la kalasi I, lomwe limapanga maziko a Shiff mu njira yopangira mphamvu. Gawoli limalumikizidwa pamodzi ndi gulu la amino la malo ogwirira ntchito kuti liyambe kusweka ndi kupanga mgwirizano. Kusiyana pakati pa ma DERA ndi ma aldolase ena ndikuti magawo omwe amapangira mphamvu ndi aldehydes ndipo amatha kuzizira mosalekeza.

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Imelo:lchen@syncozymes.com

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Tsatanetsatane wa Zamalonda

Ma tag a Zamalonda

Zokhudza Aldolase:

Pali mitundu 8 ya zinthu za aldolase (Nambala monga ES-DERA-101 ~ ES-DERA-108) yopangidwa ndi SyncoZymes. SZ-DERA ndi chida chothandiza chothandizira kupanga ma bond a carbon-carbon enantioselective, ndikupanga malo awiri a chiral pansi pa zochitika zofatsa.

Mtundu wa catalytic reaction:

Njira yothandizira:

Zambiri Zamalonda:

Ma enzyme	Khodi ya Zamalonda	Kufotokozera
Ufa wa Enzyme	ES-DERA-101~ ES-DERA-108	seti ya 8 Aldolase, 50 mg iliyonse 8 zinthu * 50mg / chinthu, kapena kuchuluka kwina
Zida Zowunikira (SynKit)	ES-DERA-800	seti ya 8 Aldolase, 1 mg iliyonse Zinthu 8 * 1mg / chinthu

Ubwino:

★ Mtundu wa substrate wokulirapo.
★ Kusintha kwakukulu.
★ Zogulitsa zochepa.
★ Zinthu zofatsa zomwe zimachitika chifukwa cha kukwiya.
★ Yosamalira chilengedwe.

Malangizo ogwiritsira ntchito:

Kawirikawiri, njira yochitira zinthu iyenera kukhala ndi substrate, yankho la buffer (pH yabwino kwambiri yochitira zinthu) ndi ES-DERA.
➢ Mitundu yonse ya ES-DERAs yogwirizana ndi machitidwe osiyanasiyana abwino kwambiri iyenera kuphunziridwa payekhapayekha.
➢ ES-DERA iyenera kuwonjezeredwa mu dongosolo lomaliza la reaction kuti ntchitoyo ipitirire.
➢ Kuchuluka kwa substrate kapena mankhwala omwe ali ndi substrate kungalepheretse ntchito ya ES-DERA. Komabe, kuletsako kungachepetsedwe powonjezera substrate.