Shangke Bio ndi Zhejiang Supor Pharmaceutical Co., Ltd. adatenga nawo gawo mu 2020 Nanjing API CHINA API Exhibition ndipo adapereka lipoti lapadera lamaphunziro pa NMN.

Dr. Zhu adayankhula kuchokera ku chitukuko cha NMN, ndipo pang'onopang'ono anatulukira chinsinsi cha mankhwala oletsa kukalamba NMN: NMN imafupikitsidwa monga β-nicotinamide mononucleotide, yomwe ili kalambulabwalo wa NAD +;Zotsatira zoyeserera zomwe zidasindikizidwa m'manyuzipepala apamwamba asayansi apadziko lonse lapansi zimatsimikizira kuti, amakhulupirira kuti zomwe zili mu NAD + m'thupi la munthu zimachepa ndi ukalamba, zomwe zimatsogolera kukalamba kuyambira zaka 30, ndi makwinya, kupumula kwa minofu, kudzikundikira mafuta, komanso chiopsezo chowonjezereka. matenda a mtima, kuthamanga kwa magazi, sitiroko, shuga, ndi matenda a Alzheimer.Kafukufukuyu adapeza kuti maselo akakhala otsika mu NAD +, amayankha pofotokoza zambiri za SLC12A8 transporter, kulola kuyamwa bwino kwa NMN kuchokera m'magazi, pomwe jini ya SLC12A8 yonyamula idapezeka kuti ikuwonetsedwa m'matenda ambiri komanso m'matumbo Zomwe zili mkati. thirakiti ndi lalitali kwambiri.M'matumbo, NMN imatengedwa mwachangu kuchokera m'matumbo ang'onoang'ono mkati mwa mphindi 2-3 ndikusinthidwa kukhala NAD + mkati mwa mphindi 10-30.

Zotsatira zotsutsana ndi ukalamba za NMN zatsimikiziridwa mwasayansi ndikuthandizidwa ndi zochitika zenizeni zenizeni.Pakalipano, dziko la Japan lasanduka dziko lomwe lavomereza mwalamulo NMN ngati chakudya chopangira chakudya.

Mu Januware 2019, NMN inali ndi zinthu 188 zokha pa netiweki yonse, ndipo pofika kumapeto kwa Ogasiti 2020, kuchuluka kwa zinthu pamaneti onse apanyumba kudaposa 2,962.Pali kuchuluka kwa zinthu, kusowa kwa miyezo yamakampani, komanso kusaganizira zachitetezo ndikuchita bwino.Kuphatikiza apo, mitundu yambiri ya NMN ilibe ukadaulo woyambira, ndipo zinthuzo zimasakanizidwa.

Msika wapadziko lonse lapansi wazinthu zolimbana ndi ukalamba (kuphatikiza magulu atatu azinthu zodzikongoletsera, zakudya ndi mankhwala oletsa kukalamba) unali wamtengo wapatali $250 biliyoni mu 2016 ndipo ukuyembekezeka kukula pa CAGR ya 5.8% kufikira $331.41 biliyoni pofika 2021 North America ndiye dera lomwe likutsogola kwambiri pamsika wothana ndi ukalamba padziko lonse lapansi, ndikutsatiridwa ndi Europe ndi Japan, ndipo Asia Pacific ikuyembekezeka kukhala dera lomwe likukula mwachangu padziko lonse lapansi mtsogolo.Pakadali pano, opanga zinthu padziko lonse lapansi a NMN akhazikika kwambiri ku China, ndipo njira zopangira zimaphatikizira kaphatikizidwe ka mankhwala, kaphatikizidwe ka mankhwala ndi enzymatic synthesis ndi njira yonse ya enzymatic.Kafukufuku wokwanira wachipatala pa ntchito zoyenera za NMN ndiye maziko akukula kwa msika wamtsogolo, ndipo kutsata malamulo ndi kukhazikitsidwa kwawo ndizo mfundo zazikuluzikulu zakukula kwa msika wamtsogolo.Coenzyme imatenga gawo lofunikira kwambiri pakupanga kagayidwe kazakudya kwamunthu, ndipo zinthu zake zimagwiritsidwa ntchito kwambiri muzakudya ndi zamankhwala.Kuphatikiza apo, coenzyme ndiye maziko azinthu zobiriwira za biopharmaceuticals.

Shangke Bio ndi bizinesi yomwe imazindikira kupanga kwamafakitale kwa coenzyme NMN/NAD/NADH/NADP/NADPH ndi zinthu zina kudzera muukadaulo wonse wa enzyme catalysis, ndipo yadutsa chiphaso cha ISO9001, SELF GRAS (US FDA ikuwunika. chitetezo chazowonjezera chakudya) Chitsimikizo chachitetezo ndi "kuyesa kwapoizoni wamkamwa" zovomerezeka zapambana mbiri yabwino pamsika, ndipo zinthuzo zimatumizidwa kudziko lonse lapansi.