Kupita patsogolo kwa kafukufuku pa kapangidwe ka enzymatic ka zinthu zomwe zingatheke kuti Clenbuterol ipangidwe mogwirizana pakati pa Norwegian University of Science and Technology ndi Shangke Biomedical

Clenbuterol, ndi agonist wa β2-adrenergic (agonist wa β2-adrenergic), wofanana ndi ephedrine (Ephedrine), nthawi zambiri amagwiritsidwa ntchito kuchipatala pochiza matenda osatha obstructive pulmonary disease (COPD). Imagwiritsidwanso ntchito ngati bronchodilator kuti ichepetse kufalikira kwa mphumu. Kumayambiriro kwa zaka za m'ma 1980, kampani yaku America ya Cyanamid inapeza mwangozi kuti ili ndi zotsatira zodziwikiratu zolimbikitsa kukula, kukonza kuchuluka kwa nyama yopanda mafuta komanso kuchepetsa mafuta, kotero idagwiritsidwa ntchito ngati clenbuterol mu ulimi wa ziweto. Komabe, chifukwa cha zotsatira zake zoyipa, European Community inaletsa kugwiritsa ntchito clenbuterol ngati chowonjezera cha chakudya kuyambira pa Januware 1, 1988. Inaletsedwa ndi FDA mu 1991. Mu 1997, Unduna wa Zaulimi wa People's Republic of China unaletsa mwamphamvu kugwiritsa ntchito ma beta-adrenergic hormones popanga chakudya ndi ziweto, ndipo Clenbuterol hydrochloride inali pamalo oyamba.

Komabe, Clenbuterol ya racemic yawonetsedwa posachedwapa kuti imachepetsa chiopsezo cha matenda a Parkinson. Kuti titsimikizire kuti ndi ma isomer ati (kapena onse awiri) omwe amachititsa izi, enantiomer ya Clenbuterol yoyera iyenera kuphunziridwa padera.